Restoring Glow to your Patients. Delivering Growth to your Practice. HALO™, the world’s first Hybrid Fractional Laser (HFL), is revolutionizing resurfacing. HALO delivers non-ablative and ablative wavelengths to the same microscopic treatment zone, giving patients results they love without the discomfort or downtime they expect. Product Overview HALO, the world’s first hybrid fractional laser, applies tunable non-ablative (1470nm) and ablative (2940nm) wavelengths to the same microscopic treatment zone to maximize results and reduce downtime. Sciton’s new technology produces targeted, reproducible, effective results that improve the appearance of numerous skin conditions. Intelligent energy delivery, combined with Dynamic Thermal Optimization, ensures precise, even, safe treatments. HALO owners love achieving maximum return on their investment while exceeding their patients’ expectations. Easy to use and virtually painless, HALO sets the standard for the future of laser resurfacing by providing a safe and powerful long-term hybrid solution. As part of the multifaceted, expandable JOULE platform, HALO provides the practitioner with a dynamic and essential component of their aesthetic toolbox. Highlights Long term sun exposure, active lifestyle and the wear and tear of everyday living results in visible signs of skin aging, including wrinkles, discoloration, scars and laxity. A fractional treatment, whether ablative or coagulative, allows the epidermis to heal quickly as long as the dermis remains intact. Ablative fractional resurfacing is a well-established treatment that vaporizes aged tissue with less thermal injury, with mild to moderate levels of morbidity and downtime. Conversely, non-ablative fractional resurfacing causes thermal injury and tissue coagulation with lower levels of morbidity. The HALO hybrid fractional laser combines ablative and non-ablative wavelengths delivered to the same microscopic treatment zone to maximize clinical results and minimize downtimes. HALO is safe and effective, while providing an enhanced patient experience. HALO Physician Benefits High revenue and profit generating procedure Consistent, predictable results in just 1-2 treatments Easy to perform and safe to delegate Off face software templates for neck, chest, and hands All Fitzpatrick skin types Fast treatments with customizable energy density settings HALO Patient Benefits More comfortable than traditional fractional resurfacing Fast healing, patients back in make-up within 24 hours Low downtime, patients are able to go back to work within a couple of days No occlusive post-care Noticeable improvement within weeks Clinical Applications Patients treated with HALO experience great improvement to the appearance of skin. They can expect remarkable results in 1-2 treatments while older, non-hybrid technology often requires 5-6 treatments to demonstrate similar texture changes delivered from HALO in terms of pigment correction. The HALO patient experience is second-to-none: the treatment is extremely comfortable, only a topical anesthetic is recommended (no nerve blocks), and patients can apply makeup within 24 hours of the procedure. HALO Indications Wrinkles and fine lines Sun damage/dyschromia Skin resurfacing Scar revision (including acne scars) Signs of aging Pigmented lesions Improves appearance of enlarged pores Medical dermatology/Actinic Keratoses HALO can treat all skin types, on face and body. Popular off-face treatments include: neck, chest, arms, hands, and legs. HALO by Sciton sets the standard for the future of laser resurfacing by providing a safe, tunable, and effective long-term hybrid option for resurfacing treatments. Science and Technology Adding tunable ablation to a non-ablative treatment creates varying effects when different levels are used. Low levels of ablation (up to 20 microns) cause faster clearance of microscopic epidermal necrotic debris (MENDs). Heavier levels of ablation (up to 100 microns) seem to create a synergistic wound healing response. The clinical effect is ablative-like results with nearly non-ablative-like healing. HALO Before and After 1 Treatment 1470 nm 400 µm coagulation, 20% density, 2940 nm 30 µm ablation, 19% density The 2940 nm wavelength targets the epidermis or top layer of the skin and is tunable between (20-100um) to precisely vaporize tissue in a controlled manner to address textural issues and pore size. The 1470 nm wavelength targets the dermis is tunable to (250-700um) to address deeper sun damage, stimulates collagenesis, and other dermal pigmentary issues. Each wavelength can be tuned independently for precise coverage and depth. HALO Technology Beyond the hybrid technology that makes HALO so unique are many features that help improve usability and safety. Features include: Integrated Cooling and Smoke Evacuation Independently tunable 1470 nm and 2940 wavelengths Dynamic Thermal Optimization DTO technology Optical Navigation Adjustable Beam Placement (ABP) Available on the expandable JOULE platform HALO offers the flexibility of completely turning off ablation for users that are not qualified to use an ablative laser (state by state regulation) or for those looking for the simplest laser treatments. Both the ablative and non-ablative laser wavelengths can be delivered in the same pass, and many permutations of depths and density coverage are possible. INTEGRATED COOLING The HALO hand piece includes integrated air cooling and smoke evacuation. The integrated cooling provides cold air across the treatment zone which provides patient comfort while smoke evacuation provides safety for the patient and operator. The integrated design makes it easy for treatments to be performed by one person. DTO TECHNOLOGY Dynamic Thermal Optimization (DTO) is built into HALO to automatically adjust the power of each individual 1470 nm pulse based on the temperature of the patient’s skin. This feature makes HALO the most precise, safe, comfortable, and consistent non-ablative technology on the market. OPTICAL NAVIGATION The high-speed optical navigation system on the HALO hand piece captures the motion of the hand piece hundreds of times every second to track the speed with extreme precision. Combining the optical navigation with sophisticated software to map the patient’s skin, the safety of the treatment increases and creates a consistent treatment from beginning to end. ABP (ADJUSTABLE BEAM PLACEMENT) Change both the size and position of the delivery beam Three beam sizes: 15 mm, 7 mm, or 4 mm Two beam placements: left or right Treat areas with distinct edges and linear scars HALO’s Physician Interface Mechanism of Action Adding tunable ablation to a non-ablative treatment creates varying effects when different levels of depth and densities are used. Using low levels of ablation (up to 20 microns) causes faster clearance of microscopic epidermal necrotic debris (MENDs). Heavier levels of ablation (up to 100 microns) create a synergistic wound healing response. The clinical effect is ablative-like results with nearly non-ablative-like healing. During a non-ablative treatment, a column of the skin called the Micro Thermal Treatment Zone (MTZ) is heated to a temperature that necroses the epidermis and denatures dermal collagen. In the first 24 hours, the basal cell layer regenerates across the MTZs, under the necrosed epidermis, and then proliferates upwards, expelling the necrosed tissue. This necrosed tissue becomes small packets of debris called Microscopic Epidermal Necrotic Debris (MENDs) that are trapped under the stratum corneum, taking between 2 to 7 to days to clear. Performing a 20-micron ablation followed by coagulation allows faster removal of MENDs. By removing the stratum corneum, the MENDs are free to exit the skin within a day of forming. This results in 1 – 2 days faster healing time as compared to non-ablative treatments. Ablating tissue creates a stronger wound healing response than just coagulating the tissue . This wound healing response can be optimized by adding more ablation during a HALO treatment. Adding up to 100 microns of ablation removes some of the tissue that would otherwise be necrosed near the surface, eliminating any MEND formation and limiting adverse events near the surface. In addition, the increased wound healing response in ablated tissue has a synergistic effect when combined with coagulated tissue though activation of Activator Protein 1 (AP-1) transcription factor leading to upregulation of Matrix Metalloproteinase (MMPs) which drive dermal remodeling . The combination of the ablated epidermis’ inflammatory response with the denaturing of the dermis’ collagen accounting for the greater, ablative-like results that are seen with a hybrid fractional treatment. HALO offers an innovative approach to resurfacing. It’s very comfortable and predictably delivers great results. It has quickly become the most utilized procedure in my practice. ARISA ORTIZ, MD | Dermatologist I recently added HALO to my practice and I have been impressed by patient comfort and low downtime, while still providing amazing results after just 1-2 treatments. It has greatly enhanced my skin revitalization practice. BARRY DIBERNARDO, MD | Plastic Surgeon